Karren is now known as the first woman in football. She was Managing Director of Birmingham City Football Club from 1993 to 2009 and during that time turned the Club's fortunes around. She took over Birmingham City FC when it was in administration, and in her first year at the helm, the Club recorded a financial trading profit. In 1996 the Club made an overall profit for the first time in modern history and in February 1997 she launched the Club on the Stock market; she was the youngest Managing Director of a PLC in the UK.
In October 2009 her business was valued at over £82million and she sold it.
In January 2010, Karren was appointed Vice Chairman of West Ham United FC. In January 2011, under her leadership campaign, WHU was awarded as preferred bidder for the Olympic Stadium. As a result her club hope to be moving there post games in 2014. Following her first 12 months at West Ham, the club made a trading profit for the first time in many years.
Karren has attracted much media attention in her career, and was the subject of an hour long documentary 'Inside Story' - The Real Life Manageress' shown on BBC 1. She has hosted her own TV show, and has also presented shows on ITV. Karren has written four books.
Karren is a columnist for The Sun newspaper; the UK's biggest selling national daily newspaper. She is also a columnist for Women & Home. She is a judge of the Cosmopolitan Women of Achievement Awards and the Sports Industry Awards, Red Magazine Women Awards, Women & Home Women Awards.
An Ambassador for The Stroke Association, WellChild and Teenage Cancer Trust, Karren is also Chair of the Mothercare Group Foundation. She has been a Board Director of Mothercare PLC, Channel 4 Television and Sport England and is currently a non-Executive Director of Arcadia. She is an honoree Fellow of the Institute of Sales and Marketing.
She was voted by Cosmopolitan as one of the 100 most powerful women in the world and in 2004 and again in 2006 attended The Queen's lunch for Women Achievers and Business Leaders. She was acknowledged as one of the most influential women in Britain by the Daily Mail and voted as one of Britainís Most Inspirational Women by Good Housekeeping magazine.
In November 2006 she won the Cosmopolitan Woman of the Year, in the category of Women Who Have Changed the World.
In March 2006 she was chosen as the team leader on BBC1's The Apprentice, for Comic Relief, where she led her team (Trinny Woodall, Jo Brand, Cheryl Cole and Maureen Lipman) to a resounding victory over the boys team (Alistair Campbell, Piers Morgan, Rupert Everett, Danny Baker and Ross Kemp) raising over £750k (the two teams together raising £1million for charity).
In December 2007 Karren was a guest on Desert Island Discs and February 2008 saw the launch of Karren Bradyís 'Today's Business Woman' magazine.
In October 2007 Karren was voted Business Woman of the Year and in November 2008 she was named as one of the top leadership role models in a national poll. This recognition was quickly followed in December 2008 when she was presented with the coveted Spirit of Everywoman Award at the NatWest Everywoman Awards, acknowledging her outstanding achievements in changing the landscape for women in business.
During January 2009, Karren presented a series of features for ITV1's GMTV called Just the Job, helping people back into work, and giving advice about looking for and retaining your job in this uncertain economic climate.
November 2010 saw Karren listed in the business category of The Sunday Telegraph's '100 Most Powerful Women in Britain', whilst she was also included in the Evening Standard's list of 'London's 1000 Most Influential People 2010', second to David Beckham in the category of Sport.
In December 2010 Dr. Karren Brady received her Doctorate from the University of Birmingham in Business studies.
In 2010 following appearances as one of Lord Sugar's interrogators on the popular BBC show 'The Apprentice', Karren has replaced Margaret Mountford as Lord Sugar's right-hand woman.
In July 2011 she won the National Reality TV Award for Best TV Judge beating Cheryl Cole, Louis Walsh and Aleshia Dixon amongst others.