Her early textile fashion designs were considered too outrageous by the traditional British manufacturers, so in 1969, she established her own retail outlet in the fashionable Fulham Road in West London. Zandra's own lifestyle has proved to be as dramatic, glamorous and extroverted as her designs. With her bright green hair (later changed to a spectacular pink and sometimes a radiant red), theatrical makeup and art jewelry, she has stamped her identity on the international world of fashion.
She was one of the new wave of British designers who put London at the forefront of the international fashion scene in the 1970s. Her designs have always been clear, creative statements, dramatic but graceful, bold but feminine and her garments have a timeless quality that makes them unmistakably a Rhodes creation. Zandra's inspiration has always been from organic material and nature. Her innovative approach to the construction of garments can be seen in her use of reversed exposed seams and in the stylistic use of jewelled safety pins and tears during the punk era.
Zandra designed for the late Diana, Princess of Wales, and continues to design for the royal and the rich and famous around the world. She has a loyal cult following in the USA. Over the years, she has had many academic and professional honours bestowed upon her and was made a Commander of the British Empire by the Queen in 1997.